详细描述

MMPSense 680 is a protease activatable fluorescent in vivo imaging agent that is activated by key matrix metalloproteinases (MMPs) including MMP-2, -3, -9 and -13. MMPSense 680 is optically silent in its unactivated state and becomes highly fluorescent following protease-mediated activation. 

MMP activity is involved in many disease-related processes including cancer progression, invasion and metastasis, rheumatoid arthritis, pulmonary diseases and areas of cardiovascular disease. MMPSense 680 may be used to monitor the progression of these diseases or to evaluate the potential therapeutic efficacy of drugs targeting the underlying mechanisms involved in these diseases. 

“For laboratory use only. This product is intended for animal research only and not for use in humans.”

Get a quote or request more information on any of our reagents.

Additional Resources
In Vivo University
In Vivo Reagents Citations Library
In Vivo Imaging Systems & Software