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Biotin anti-human CD38；Clone#：HIT2Host/Isotype：Mouse IgG1, κ   

详细描述

Clone: HIT2
Isotype: Mouse IgG1, κ
Workshop Number: III 155
Reactivity: Human, Cross-Reactivity: Chimpanzee
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Application:

FC - Quality tested
IHC - Reported in the literature
Application Notes:

Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections.
Recommended Usage:

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Application References:

1. Kishimoto T, et al. Eds. 1997. Leucocyte Typing VI. Garland Publishing Inc. London.
2. Dieu M. 1998. J. Exp. Med. 188:373.
3. Esser M, et al. 2001. J. Virol. 75:6173.
4. Jeannin P, et al. 1999. J. Immunol. 162:2044.
5. Kapsogeorgou EK, et al. 2001. J. Immunol. 166:3107.
6. van der Voort R, et al. 1997. J. Exp. Med. 185:2121. (IHC)
7. Bende RJ, et al. 2003. Am. J. Pathol. 162:105.
8. Lehner M, et al. 2008. J. Leukoc. Biol. 83:883. PubMed
9. Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
Human peripheral blood lymphocytes stained

Human peripheral blood lymphocytes stained with biotinylated HIT2, followed by Sav-PE

Description:

CD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscles, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.
Other Names: T10, ADP-ribosyl cyclase
Structure: ADP-ribosyl cyclase, ectoenzyme, type II glycoprotein, 45 kD
Distribution: T cells, B cells, NK, myeloid, plasma, and dendritic cells
Function: Ecto-ADP-ribosyl cyclase, calcium signaling, cell activation
Ligand Receptor: CD31, hyaluronic acid
Antigen References:

1. Ferrero E, et al. 1999. J. Leukoc. Biol. 65:151.
2. Lund F, et al. 1995. Immunol. Today 16:469.

  • 目录号：2117585
  • 品牌：Sony Biotechnology
  • 规格：25μg
  • 目录价：￥2064.00
  • 市场价格：￥1341.60
  • 会员价格：￥1279.68
  • 数量：

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