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Alexa Fluor® 647 anti-human CD154;Isotype:Mouse IgG1, κ;Reactivity:Human, Cross-Reactivity: C   

详细描述

Antibodies Single
Sony
24-31
Flow Cytometry
Mouse IgG1, κ
Human
Alexa Fluor® 647 anti-human CD154
Description

CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.

Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
Recommended Usage Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 microL per million cells or 5 microL per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633nm / 635nm.
References

1. Brams P, et al. 2001. Int. Immunopharmacol. 1:277. (Block, IF)
2. Rushworth SA, et al. 2002. Transplantation 73:635. (Block)
3. Berner B, et al. 2000. Ann. Rheum. Dis. 59:190. (IF)
4. Nordström T, et al. 2006. J. Leukocyte Biol. 79:319. (Block)
5. Zhang AL, et al.2007. Blood doi:10.1182/blood-2007-02-076364. (Block) PubMed
6. Kuchen S, et al. 2007. J. Immunol. 179:5886.
7. Matus-Nicodermos R, et al. 2011. J. Immunol. 186:2164. PubMed

  • 目录号：2154090
  • 品牌：Sony Biotechnology
  • 规格：100tests
  • 目录价：￥5421.00
  • 市场价格：￥3523.65
  • 会员价格：￥3361.02
  • 数量：

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