详细描述

NeuroBase A supports neuronal growth in feeder-independent cultures of adult brain neurons and neuronal tumor cell lines. The basal medium is formulated without glutamate and aspartate. NeuroBase A may be supplemented with chemically defined additives, such as NCS21, or serum.

NeuroBase A 支持成脑神经元和神经元肿瘤细胞系在无饲养层细胞培养条件下的神经元生长。该基础培养基不含谷氨酸和天冬氨酸。NeuroBase A 可添加化学成分明确的添加剂（如 NCS21）或血清进行补充。

产品描述
NeuroBase 产品线包含两种不同的基础培养基，用于培养不同类型的神经元细胞。该产品线还配有 NCS21 和 N2 这两种化学成分明确的添加剂，形成了完整的产品组合。
NeuroBase A 是一种专门配制的基础培养基，旨在促进出生后和成脑神经元的生长。与传统依赖星形胶质细胞滋养层支持的方法不同，NeuroBase A 允许这些成熟神经元及神经元肿瘤细胞系实现无饲养层培养。这为研究成体神经元细胞的独特特性和功能提供了更可控的环境。
主要特点

1. 专为成脑神经元和肿瘤细胞系优化：NeuroBase A 专为满足成脑神经元和神经元肿瘤细胞系的特定需求而设计，能够促进其在培养过程中的维持与成熟。
2. 实现无饲养层独立生长：通过消除对星形胶质细胞饲养层的依赖，NeuroBase A 简化了培养流程，使研究人员能够专注于成体神经元细胞本身特性的研究。
3. 不含神经递质：NeuroBase A 的配方中不含谷氨酸和天冬氨酸。这一独特特性使得研究神经递质在成脑功能及信号通路中的具体作用成为可能。
4. 补充物添加灵活多变：根据具体的研究需求，NeuroBase A 可进一步添加多种补充物。兼容的补充物包括：

• NCS21：一种广泛使用的无血清补充剂，可为细胞提供明确且稳定的生长环境。
• N2：一种基于 Bottenstein N2 配方开发的无血清、化学成分明确的补充剂。
• 血清：尽管成分不那么明确，但在某些特定应用中，研究人员可能会选择添加胎牛血清 (FBS) 或其他类型的血清。

The NeuroBase product line consists of two different basal media for cultivation of different types of neuronal cells. The product line is complemented by two chemically-defined additives, NCS21- and N2-supplement.

NeuroBase A is a specialized basal medium formulated to boost growth of postnatal and adult brain neurons. Unlike traditional methods that rely on supportive astrocyte feeder cells, NeuroBase A allows feeder-independent cultivation of these mature neurons and neuronal tumor cell lines. This provides a more controlled environment for investigating the unique properties and functions of adult neuronal cells.

Key Features:

1. Especially for Adult Brain Neurons and Tumor Cell Lines: NeuroBase A is specifically formulated to meet the specific needs of adult brain neurons and neuronal tumor cell lines, promoting their maintenance and maturation in culture.
2. Independent Growth: By eliminating the requirement for an astrocyte feeder layer, NeuroBase A simplifies the culturing process and allows to focus on the intrinsic properties of adult neurons.
3. Neurotransmitter-free: NeuroBase A is formulated without glutamate and aspartate. This unique feature enables investigating the specific roles of neurotransmitters in adult brain function and signaling pathways.
4. Versatility in Supplementation: NeuroBase A can be further supplemented with various additives depending on the specific research needs. Compatible supplements include:

• NCS21: A widely used serum-free supplement providing a defined and consistent growth environment.
• N2: A serum-free, chemically defined supplement based on Bottenstein’s N2 formulation
• Serum: While less defined, some researchers may prefer using fetal bovine serum (FBS) or other types of serum for specific applications.