G-418 Sulfate, Solution, 100 % Activity (50 mg/ml)G-418硫酸盐溶液，100%活性（50 mg/ml）
详细描述
G-418 Sulfate Solution is used as a selection antibiotic in cell culture. It blocks polypeptide synthesis. Transformed cells containing the neomycin resistance genes neo can be selected.
G-418硫酸盐溶液在细胞培养中用作筛选抗生素。它通过阻断多肽合成来发挥作用，可用于筛选含有新霉素抗性基因（neo）的转化细胞。
Storage:≤-15°C
Sterility:Sterile-filtered
产品描述
G-418硫酸盐溶液用于稳定转染了新霉素抗性基因的真核细胞的筛选与维持培养。
G-418硫酸盐是一种氨基糖苷类抗生素，与庆大霉素类似，对真核细胞和原核细胞均有毒性。它由绛红小单孢菌产生，作用机制是与核糖体结合，从而抑制原核和真核细胞中的蛋白质合成。
Description
G-418 Sulfate Solution is used in the selection and maintenance of eukaryotic cells stably transfected with neomycin resistance genes.
G-418 Sulfate is an aminoglycoside antibiotic, related to Gentamicin, and exhibits toxicity towards both eukaryotic and prokaryotic cells. It is produced by Micromonospora rhodorangea and acts by binding the ribosome, thus inhibiting protein synthesis in both prokaryotic and eukaryotic cells.
引用文献：
Cell-based and isoform-selective G protein-coupled receptor kinase assays for comprehensive inhibitor evaluation
… FBS; Capricorn Scientific, FBS-11A) and 1% penicillin/streptomycin (Capricorn Scientific,
PS… additionally received 0.5 mg/ml G418 (Capricorn Scientific, G418-B) as selection antibiotic. …
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continuously cultivated in cell culture growth media containing 0.2 g/l G418. The cells were …
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50 mg/ml) were obtained from Capricorn (Capricorn Scientific, Ebsdorfergrund, Germany), …
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Scientific, G418-Q) for ∼14 days to select for stably transfected cells. Cells were …
Visualizing extracellular vesicle-mediated RNA transfer using a novel metabolic labeling approach
in the presence of G418 (500 µg/mL, Capricorn Scientific) 29 . Cells were maintained under …
